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HU-210 is a synthetic agonist analog of Δ9-THC, which is the primary psychoactive component of marijuana. HU-210 is a potent central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptor agonist. It binds to neuroblastoma cell membrane CB1 receptors with about the same affinity as CP 55,940. In mouse behavior models (hypothermia, analgesia, hypoactivity, and catalepsy) the ED50 is 5-20 μg/kg.
HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. how to make hu-210,hu-210 reddit,hu-210 psychonaut,hu-211
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HU-210 is a synthetic cannabinoid that was first synthesized in 1988 from (1R,5S)-myrtenol by a group led by Raphael Mechoulam at the Hebrew University. how to make hu-210,hu-210 reddit,hu-210 psychonaut,hu-211
HU-210 is 100 to 800 times more potent than natural THC from cannabis and has an extended duration of action. HU-210 is the (–)-1,1-dimethylheptyl analog of 11-hydroxy- Δ8– tetrahydrocannabinol; in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol. The abbreviation “HU” stands for Hebrew University.
HU-210, the (–) enantiomer of 11-OH-D8-THC-DMH, has almost all of the cannabinoid activity, while the (+) enantiomer, known as HU-211, is inactive as a cannabinoid and instead acts as an NMDA antagonist having neuroprotective effects.
Description: Highly potent cannabinoid receptor agonist
Chemical Name: (6aR)-trans-3-(1,1-Dimethylheptyl)-6a,7,10,10a-tetrahydro-1-hydroxy-6,6-dimethyl-6H-dibenzopyran-9-methanol
Purity: ≥98% (HPLC)
HU 210 is a highly potent cannabinoid receptor agonist (Ki values are 0.061 and 0.52 nM at cloned human CB1 and CB2 receptors respectively). Induces spatial memory deficits and suppresses hippocampal firing rates in rats. Also displays agonist activity at GPR55 (EC50 = 26 nM).
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